The MSAFP test can screen for several conditions, including:
1. [Neural Tube Defects](https://): High levels of AFP can indicate neural tube defects, such as spina bifida or anencephaly, where the neural tube fails to close properly during early fetal development. 2. [Down Syndrome](https://): Low levels of AFP, combined with other markers, can indicate a higher risk of Down syndrome, a genetic disorder caused by an extra copy of chromosome 21. 3. [Abdominal Wall Defects](https://): Elevated AFP levels can also suggest abdominal wall defects like gastroschisis or omphalocele, where the abdominal organs develop outside the fetal body. 4. [Multiple Gestations](https://): High AFP levels can be a sign of multiple gestations, such as twins or triplets, as more AFP is produced with more than one fetus. 5. [Other Chromosomal Abnormalities](https://): The test may also help in identifying other chromosomal abnormalities when used in conjunction with additional screening tests.
