While proteomics holds great promise, it also faces several challenges:
1. Sample Size and Variability: Neonatal samples are often small and can vary significantly, making it difficult to obtain consistent results. 2. Complexity of the Proteome: The neonatal proteome is highly dynamic and complex, requiring advanced techniques and bioinformatics tools for comprehensive analysis. 3. Clinical Translation: Bridging the gap between proteomic findings and clinical applications remains a challenge. More research is needed to validate biomarkers and integrate them into routine neonatal care.