There are several unique challenges in pediatric therapeutic target identification:
Ethical Considerations: Involving children in research poses ethical dilemmas, requiring stringent ethical guidelines and parental consent. Limited Sample Sizes: Pediatric diseases often have smaller patient populations, making it difficult to conduct large-scale studies. Developmental Differences: The physiological differences between children and adults mean that findings in adults cannot always be extrapolated to children. Diverse Age Groups: The pediatric population spans from neonates to adolescents, necessitating age-specific considerations for therapeutic interventions.
