What are the Key Steps in Identifying Therapeutic Targets?
The process of identifying therapeutic targets involves several key steps:
Understanding Disease Pathophysiology: A thorough understanding of the disease mechanism is essential. This includes studying genetic, molecular, and cellular aspects of the disease. Biomarker Identification: Identifying biomarkers that indicate disease presence or progression helps in pinpointing potential targets. Target Validation: Once a potential target is identified, it must be validated through preclinical studies and clinical trials to ensure it plays a critical role in the disease. Clinical Trials: Conducting clinical trials specific to pediatric populations to test the safety and efficacy of the therapeutic intervention.
