Several factors can lead to abnormal PT levels in children, including:
Liver disease: The liver produces most clotting factors, so any liver dysfunction can prolong PT. Vitamin K deficiency: Vitamin K is essential for synthesizing clotting factors, and its deficiency can increase PT. Medications: Certain drugs like warfarin and heparin can affect clotting times. Genetic disorders: Conditions like hemophilia and von Willebrand disease can prolong PT. Malnutrition: Poor nutrition can lead to deficiencies in essential vitamins and minerals necessary for clotting.
