What are the Treatment Options for Pediatric Cancers Involving Oncogenes?
Treatment strategies for pediatric cancers involving oncogenes often include a combination of surgery, chemotherapy, and radiation therapy. Additionally, targeted therapies have shown promise. For instance, tyrosine kinase inhibitors like imatinib are effective in treating cancers with the BCR-ABL fusion gene. Similarly, ALK inhibitors can be used for neuroblastomas with ALK gene mutations. These targeted therapies specifically inhibit the activity of oncogenes, thereby reducing cancer cell proliferation.