Which Pediatric Cancers are Commonly Associated with Oncogenes?
Several pediatric cancers are linked to specific oncogenes. For instance:
- Neuroblastoma: Often associated with MYCN amplification. - Acute Lymphoblastic Leukemia (ALL): Frequently involves alterations in the BCR-ABL fusion gene. - Retinoblastoma: Associated with mutations in the RB1 gene, which can function as an oncogene. - Rhabdomyosarcoma: Linked to mutations in the PAX3-FKHR fusion gene.
