What are the long-term implications for children with TP53 mutations?
Children with TP53 mutations face a lifelong increased risk of developing multiple cancers. Therefore, they require ongoing surveillance and a tailored follow-up plan that includes regular imaging and screenings. Preventive measures and lifestyle modifications may also be recommended to reduce the risk of cancer development. Genetic counseling for family planning and risk assessment for relatives is also a crucial aspect of managing TP53 mutations.
