The Crnic Institute focuses on several key research areas: 1. Genetic and Molecular Research: Understanding the extra chromosome 21 and its effects on cellular function. 2. Neurodevelopmental Studies: Investigating brain development and cognitive function in children with Down syndrome. 3. Immunological Research: Exploring the immune system dysfunctions often seen in DS patients. 4. Clinical Trials: Conducting trials to test new therapies and interventions.