What are the Clinical Applications of DNA Methylation Analysis?
There are multiple clinical applications of DNA methylation analysis in pediatrics: - Diagnosis: Helps diagnose genetic disorders like Prader-Willi syndrome and Angelman syndrome. - Prognosis: Assesses prognosis in pediatric cancers such as neuroblastoma and leukemia. - Therapeutic Targets: Identifies potential targets for epigenetic therapies, which can modify aberrant methylation patterns.