What Are the Challenges in Pediatric Dose Adjustment?
Adjusting doses in pediatric patients comes with several challenges:
Lack of Clinical Trials: Many medications are not extensively studied in pediatric populations, leading to off-label use. Variable Pharmacokinetics: Rapid developmental changes can make it difficult to predict drug behavior. Compliance: Children may have difficulty adhering to complex dosing regimens. Formulation Issues: Medications may not be available in child-friendly formulations.
