What are the Challenges in Neonatal Transplantation?
Transplantation in neonates presents unique challenges due to their immature immune system, small size, and the presence of comorbid conditions. Some of the primary challenges include:
Immature Immune System: The neonatal immune system is not fully developed, which can affect both the risk of rejection and the ability to fight infections. Size Compatibility: Finding appropriately sized donor organs can be difficult, as neonates require smaller organs. Immunosuppressive Therapy: Managing immunosuppression in neonates is complex due to their ongoing development and potential side effects of the medications.
