What are the challenges and limitations of prophylactic antifungals in Pediatrics?
Challenges and limitations include: - Development of resistance: Prolonged use can lead to antifungal resistance. - Adverse effects: Potential for significant toxicity. - Cost and accessibility: High cost can be a barrier in resource-limited settings. - Compliance: Ensuring adherence to prophylactic regimens can be challenging, particularly in outpatient settings.
