Several factors can contribute to neonatal hypoglycemia:
1. Prematurity: Premature infants have limited glycogen stores and immature metabolic pathways. 2. Maternal Diabetes: Infants born to diabetic mothers may have excessive insulin production leading to hypoglycemia. 3. IUGR: Infants with intrauterine growth restriction have reduced glycogen and fat stores. 4. Sepsis: Infection can increase metabolic demands and deplete glucose levels. 5. Endocrine Disorders: Conditions like congenital hyperinsulinism can lead to excessive insulin secretion.