multiplex ligation dependent probe amplification (mlpa)

What are the Advantages of MLPA?

MLPA offers several advantages in the context of pediatric diagnostics:
High Sensitivity and Specificity: It can detect even small deletions and duplications with high precision.
Efficiency: The technique allows for the simultaneous analysis of multiple targets in a single reaction.
Cost-Effective: Compared to other methods like whole genome sequencing, MLPA is more affordable and quicker, making it suitable for routine clinical practice.
Versatility: MLPA can be adapted to analyze various types of genetic material, including genomic DNA and RNA.

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