What are Some Key Transcription Factors in Pediatric Development?
Some key transcription factors involved in pediatric development include:
SOX2: Plays a critical role in the maintenance of stem cells and is essential for early embryonic development. NKX2-5: Important for cardiac development and mutations can lead to congenital heart diseases. FOXP3: Crucial for the development and function of regulatory T cells, and its mutations can result in immunodeficiency disorders. HNF1A: Involved in liver and pancreatic development, and mutations can cause diabetes in children.
