How is Volume of Distribution Calculated in Pediatrics?
The general formula for calculating Vd is: Vd = (Amount of drug in the body) / (Plasma drug concentration) In pediatrics, adjustments must be made for body weight and age. Pediatric dosing calculators and age-specific dosing charts are often used to ensure accurate calculations. Clinicians must also consider the unique pharmacokinetic characteristics of pediatric patients when determining Vd.
