How is Retinoblastoma Protein Related to Neonatal Disorders?
While retinoblastoma protein is primarily studied in the context of cancer, its role in cell cycle regulation means it can be involved in various neonatal disorders where cell proliferation and differentiation are affected. For example, mutations in the RB1 gene can lead to conditions like congenital retinoblastoma, which is a form of eye cancer present at birth. Additionally, dysregulation of pRb can be implicated in developmental anomalies affecting multiple organ systems.