Diagnosis of GVHD in neonates involves a combination of clinical evaluation, laboratory tests, and sometimes, biopsy. Key diagnostic steps include:
Clinical assessment: Detailed examination of skin, liver, and gastrointestinal symptoms. Laboratory tests: Blood tests to check liver function, complete blood count, and other relevant parameters. Biopsy: In some cases, a skin or gastrointestinal biopsy may be necessary to confirm the diagnosis.