Fluid requirements for neonates vary based on several factors, including gestational age, postnatal age, weight, and clinical condition. Typically, fluid volume is calculated in milliliters per kilogram per day (mL/kg/day). For instance, a term neonate might require 60-80 mL/kg/day initially, increasing to 150 mL/kg/day by the end of the first week. Premature infants usually require higher initial volumes due to their larger surface area relative to body weight and increased insensible water loss.