The diagnosis of DIC in neonates is complex and involves a combination of clinical assessment and laboratory tests. Key diagnostic tests include a complete blood count (CBC), coagulation profile (including PT, aPTT, and fibrinogen levels), and measurement of D-dimer and fibrin degradation products (FDPs). Elevated levels of D-dimer and FDPs, along with decreased fibrinogen and platelet counts, are indicative of DIC.