The diagnosis of cerebral malaria can be challenging due to its non-specific early symptoms. However, it is typically confirmed through a combination of clinical evaluation and laboratory tests. Blood smears to detect the presence of Plasmodium falciparum parasites, rapid diagnostic tests (RDTs), and polymerase chain reaction (PCR) are commonly used methods. Additionally, lumbar puncture may be performed to rule out other causes of coma such as bacterial or viral meningitis.
