The process involves several key steps: 1. Defining the Research Question: Clearly state the objectives and hypotheses. 2. Literature Search: Conduct a comprehensive search of databases like PubMed and Cochrane Library to identify relevant studies. 3. Inclusion and Exclusion Criteria: Establish criteria to include or exclude studies based on factors like study design, population, and outcomes. 4. Data Extraction: Collect data from the selected studies. 5. Statistical Analysis: Use statistical methods to combine data and assess heterogeneity. 6. Interpretation: Draw conclusions based on the combined data.