The process of tissue remodeling involves several key steps:
1. Inflammation: Following an injury or stress, the affected area undergoes an inflammatory response. This process helps to remove damaged cells and initiate healing. 2. Cell Proliferation and Differentiation: New cells are produced to replace damaged ones. Stem cells play a pivotal role in generating various cell types needed for tissue repair. 3. Extracellular Matrix (ECM) Remodeling: The ECM, a network of proteins and other molecules, provides structural support to tissues. Remodeling of the ECM involves the synthesis and degradation of its components to accommodate new tissue formation. 4. Apoptosis: Programmed cell death, or apoptosis, removes unnecessary or damaged cells, ensuring healthy tissue development.
