nkx2 5

How does NKX2-5 affect heart development?

NKX2-5 is essential in the early stages of heart development. It regulates the expression of other genes involved in the formation of the heart's structure and function. Disruptions in NKX2-5 can lead to various heart defects, including atrial septal defects (ASDs), ventricular septal defects (VSDs), and Tetralogy of Fallot.

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