How Does Hypoxic-Ischemic Encephalopathy Affect Neurogenesis?
Hypoxic-Ischemic Encephalopathy (HIE) occurs due to reduced oxygen and blood flow to the brain during birth. This condition can severely impair neurogenesis by causing neuronal death and disrupting the proliferation and differentiation of neural stem cells. The resulting brain damage can lead to long-term cognitive and motor deficits.