The process of absorption changes as children grow and develop. For instance:
Neonates and infants have a higher gastric pH, which can impact the absorption of acid-labile drugs. Gastrointestinal motility is slower in neonates, leading to prolonged drug exposure in the gut. Preterm infants may have underdeveloped enzyme systems, affecting nutrient and drug absorption. As children grow, their enzymatic activity and gastrointestinal motility gradually reach adult levels.