While both silicone-based and water-based lubricants are used in medical settings, they have different properties that make them suitable for specific applications. Silicone-based lubricants are longer-lasting and more resistant to water, making them ideal for prolonged procedures or use in moist environments. On the other hand, water-based lubricants are easier to clean and less likely to cause staining, making them suitable for quick applications and scenarios where frequent reapplication is necessary.