neuroprotective agents

How Do These Agents Work?

The mechanisms of action for neuroprotective agents can vary:
- Magnesium Sulfate: It acts by stabilizing cell membranes and reducing excitotoxicity, a process where excessive glutamate damages neurons.
- Therapeutic Hypothermia: Cooling reduces metabolic demand and slows down the cascade of damaging biochemical processes that follow a brain injury.
- Erythropoietin: It promotes cell survival, reduces inflammation, and stimulates neurogenesis.
- Melatonin: It scavenges free radicals and decreases oxidative stress, thereby protecting neurons.
- Allopurinol: It inhibits xanthine oxidase, an enzyme involved in the production of reactive oxygen species, thus reducing oxidative stress.

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