Prenatal Care: Regular check-ups and managing maternal health conditions can reduce risks. Safe Delivery Practices: Ensuring skilled obstetric care to minimize birth trauma and hypoxia. Vaccinations: Protecting against infections like rubella that can cause congenital CNS malformations. Newborn Screening: Early identification of metabolic disorders through routine screening. Preventive Measures: For at-risk pregnancies, preventive measures like antenatal steroids can be beneficial.