How are Prostaglandins Used in Neonatal Disorders?
In neonates, particularly those with congenital heart defects, prostaglandin E1 (PGE1) is used to maintain the patency of the DA. This is vital in conditions such as Transposition of the Great Arteries (TGA) or Hypoplastic Left Heart Syndrome (HLHS), where adequate mixing of oxygenated and deoxygenated blood is necessary until surgical intervention.