The identification of prognostic biomarkers involves several steps, including:
1. Discovery Phase: This phase involves studying biological samples from patients to identify potential biomarkers. Techniques such as genomics, proteomics, and metabolomics are commonly used. 2. Validation Phase: Potential biomarkers are validated in larger, independent cohorts to confirm their prognostic value. 3. Clinical Implementation: Once validated, biomarkers are integrated into clinical practice, often through the development of diagnostic tests or panels.
