The diagnostic process typically involves a combination of clinical suspicion, laboratory tests, and imaging studies. Key steps include:
Blood glucose and insulin levels: Persistent hypoglycemia with inappropriately high insulin levels can suggest an insulinoma. 72-hour fasting test: This test is considered the gold standard for diagnosing insulinomas. It involves monitoring the patient while fasting to observe the onset of hypoglycemia and the corresponding insulin levels. Imaging studies: Techniques like MRI, CT scans, and endoscopic ultrasound can help localize the tumor.