How are Antifungal Agents Selected for Use in Neonates?
The choice of antifungal agent depends on several factors, including the type of fungal pathogen, the site of infection, and the neonate's overall health. Fluconazole is commonly used for prophylaxis and treatment of superficial infections, while amphotericin B is often reserved for severe or invasive infections. Echinocandins like micafungin are increasingly used due to their efficacy and favorable safety profile.