Why is HLA Matching Important in Neonatal Disorders?
Neonates, or newborns, have underdeveloped immune systems, making them particularly vulnerable to infections and diseases. HLA matching is crucial in situations like stem cell transplantation, where a donor's cells are used to replace damaged or diseased cells in the neonate. Proper HLA matching can reduce the risk of graft-versus-host disease (GVHD) and increase the chances of successful engraftment.