Neonates, especially those in neonatal intensive care units (NICUs), are particularly vulnerable to CoNS infections due to their immature immune systems. Factors such as low birth weight, underdeveloped skin barriers, and the frequent use of invasive devices like catheters and ventilators further increase their risk. Premature infants are at the highest risk because of their extended stay in NICUs and the multiple medical interventions they often require.
