pediatric adverse drug reactions

Why are Children More Susceptible to ADRs?

Children are not just "small adults"; their bodies process drugs differently due to various factors such as immature organ systems, varying body composition, and metabolic rates. For instance, liver enzyme activity and kidney function, which are crucial for drug metabolism and excretion, are not fully developed in young children. This can lead to either under or over-exposure to medications, increasing the risk of ADRs.

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