The Coombs test is indicated in various pediatric scenarios:
Hemolytic Disease of the Newborn (HDN): To detect maternal antibodies against fetal red blood cells. Neonatal Jaundice: To identify the cause of jaundice, especially if hemolysis is suspected. Autoimmune Hemolytic Anemia: To detect the presence of autoantibodies against red blood cells. Transfusion Reactions: To screen for compatibility issues before blood transfusions.