HFVs are often indicated in neonates with severe respiratory conditions that do not respond well to conventional ventilation. Specific indications include:
1. Severe Respiratory Distress Syndrome (RDS): Particularly in preterm infants who are at a higher risk of lung damage. 2. Meconium Aspiration Syndrome (MAS): To reduce the risk of barotrauma and chemical pneumonitis. 3. Persistent Pulmonary Hypertension of the Newborn (PPHN): To improve oxygenation and reduce pulmonary vascular resistance. 4. Air Leak Syndromes: Such as pneumothorax, where conventional ventilation might exacerbate the condition.