What role do miRNAs play in Congenital Heart Disease?
miRNAs are critical in heart development and function. Dysregulated miRNA expression can lead to congenital heart defects in children. For example, miR-1 and miR-133 are known to be involved in cardiac muscle development and their abnormal expression is linked to various congenital heart defects. Understanding these miRNAs can help in early diagnosis and treatment strategies for affected children.