What Role Do Long Non-Coding RNAs Play in Pediatric Diseases?
Long non-coding RNAs (lncRNAs) are longer than 200 nucleotides and have diverse roles in gene regulation. In pediatrics, lncRNAs are implicated in diseases such as pediatric leukemia and congenital anomalies. For instance, dysregulation of the lncRNA HOTAIR has been associated with poor prognosis in pediatric leukemia.
