Trousseau's sign is a clinical sign that indicates latent or overt tetany, typically due to hypocalcemia. It is named after the French physician Armand Trousseau. The sign is elicited by inflating a blood pressure cuff on the upper arm to a level above the systolic pressure for several minutes. A positive Trousseau's sign is indicated by carpal spasm, which involves flexion at the wrist and metacarpophalangeal joints, extension of the fingers, and flexion of the thumb over the palm.