What is Transient Myeloproliferative Disorder (TMD)?
Transient myeloproliferative disorder (TMD) is a clonal proliferation of megakaryoblasts that primarily affects newborns, particularly those with Down syndrome (trisomy 21). Unlike other myeloproliferative disorders, TMD is characterized by its self-limiting nature, typically resolving spontaneously within the first few months of life.