The HPV vaccine is a vaccine designed to protect against the Human Papillomavirus (HPV), which is a group of more than 200 related viruses. Some types of HPV can cause cervical cancer, genital warts, and other less common but serious cancers such as those of the oropharynx, anus, and penis. The vaccine is most effective when administered before exposure to the virus, which is why it is recommended for preteens.