What is Persistent Pulmonary Hypertension of the Newborn?
Persistent Pulmonary Hypertension of the Newborn (PPHN) is a serious neonatal disorder characterized by the failure of the normal circulatory transition that occurs after birth. In a typical newborn, the circulatory system transitions from fetal circulation, where blood bypasses the lungs, to postnatal circulation, where the lungs oxygenate the blood. In cases of PPHN, the pulmonary vessels remain constricted, causing a high pulmonary vascular resistance. This results in reduced blood flow to the lungs and inadequate oxygenation of the blood.
