Infiltration refers to the accidental leakage of intravenous (IV) fluids or medications into the surrounding tissue instead of into the bloodstream. This can occur due to a variety of reasons, such as improper IV insertion, dislodgement of the IV catheter, or fragile veins in neonates. Infiltration is a common complication in neonatal intensive care units (NICUs) and can lead to various complications if not addressed promptly.