What factors influence the need for dosing adjustments in children?
Several factors influence the need for dosing adjustments in children: - Age: Neonates, infants, and adolescents all have different metabolic rates. - Weight and BSA: Helps in calculating accurate doses. - Organ Function: Immature liver and kidney functions in younger children affect drug metabolism and excretion. - Disease State: Certain conditions may require dose modifications. - Drug Formulation: Liquid formulations may be preferred for precise dosing in younger children.
