production of surfactant

What Factors Influence Surfactant Production?

Several factors can influence surfactant production in neonates:
Gestational age: The most critical factor, as surfactant production increases with gestational age.
Genetic factors: Mutations in genes responsible for surfactant production can lead to deficiencies.
Infections: Prenatal infections can impair surfactant production and function.
Maternal diabetes: Can delay surfactant production in the fetus.
Antenatal corticosteroids: Administered to pregnant women at risk of preterm birth can accelerate surfactant production.

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