Several factors can influence surfactant production in neonates:
Gestational age: The most critical factor, as surfactant production increases with gestational age. Genetic factors: Mutations in genes responsible for surfactant production can lead to deficiencies. Infections: Prenatal infections can impair surfactant production and function. Maternal diabetes: Can delay surfactant production in the fetus. Antenatal corticosteroids: Administered to pregnant women at risk of preterm birth can accelerate surfactant production.