Placental transfer can be influenced by multiple factors including maternal health, placental health, and the presence of any [placental disorders](https://). Conditions such as [pre-eclampsia](https://), [diabetes](https://), and [intrauterine growth restriction (IUGR)](https://) can significantly affect the efficiency of placental transfer. Additionally, the thickness of the placental barrier and the surface area available for exchange also play vital roles.