What Conditions in Pediatrics Can Benefit from Epigenetic Therapies?
Several pediatric conditions could benefit from epigenetic therapies:
- Pediatric Cancers: Diseases such as leukemia and neuroblastoma have shown responsiveness to epigenetic drugs like DNA methyltransferase inhibitors and histone deacetylase inhibitors. - Congenital Heart Disease: Research indicates that epigenetic modifications play a role in heart development and congenital anomalies, suggesting potential therapeutic targets. - Neurodevelopmental Disorders: Conditions like autism spectrum disorder and Rett syndrome have epigenetic underpinnings that could be targeted by these therapies.
